Worked example

Reconstitution - practice problem 9

The prescriber orders 500 mg of ampicillin IV. The vial directs: add 2 mL of diluent to yield 250 mg/mL.

Ordered dose500 mg
After reconstitution250 mg/mL
Diluent2 mL

How many milliliters should the nurse draw up?

Answer: 2 mL

Step-by-step solution

1. Read the concentration after reconstitution
Add 2 mL diluent → 250 mg per 1 mL
2. Set up dimensional analysis so mg cancels
500 mg × ( 1 mL ÷ 250 mg )
3. Cancel mg and solve
= 500 ÷ 250 mL
= 2 mL

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