Worked example

Reconstitution - practice problem 5

The prescriber orders 250 mg of ceftriaxone IM. A 1 g vial directs: add 3.6 mL of diluent to yield 250 mg/mL.

Ordered dose250 mg
Vial1 g
Diluent3.6 mL
After reconstitution250 mg/mL

How many milliliters should the nurse draw up?

Answer: 1 mL

Step-by-step solution

1. Read the concentration after reconstitution
Add 3.6 mL diluent → 250 mg per 1 mL
2. Set up dimensional analysis so mg cancels
250 mg × ( 1 mL ÷ 250 mg )
3. Cancel mg and solve
= 250 ÷ 250 mL
= 1 mL

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