Examples · Reconstitution
Worked example
Reconstitution - practice problem 13
The prescriber orders 500 mg of methylprednisolone IV. A 500 mg vial directs: add 8 mL of diluent to yield 62.5 mg/mL.
Ordered dose500 mg
Vial500 mg
Diluent8 mL
After reconstitution62.5 mg/mL
How many milliliters should the nurse draw up?
Answer: 8 mL
Step-by-step solution
1. Read the concentration after reconstitution
Add 8 mL diluent → 62.5 mg per 1 mL
2. Set up dimensional analysis so mg cancels
500 mg × ( 1 mL ÷ 62.5 mg )
3. Cancel mg and solve
= 500 ÷ 62.5 mL
= 8 mL
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