Examples · Reconstitution
Worked example
Reconstitution — practice problem 13
The prescriber orders 375 mg of cefazolin IV. The vial directs: add 2 mL of diluent to yield 250 mg/mL.
Ordered dose375 mg
After reconstitution250 mg/mL
Diluent2 mL
How many milliliters should the nurse draw up?
Answer: 1.5 mL
Step-by-step solution
1. Read the concentration after reconstitution
Add 2 mL diluent → 250 mg per 1 mL
2. Set up dimensional analysis so mg cancels
375 mg × ( 1 mL ÷ 250 mg )
3. Cancel mg and solve
= 375 ÷ 250 mL
= 1.5 mL
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